重症肿瘤患者肠道功能评估与血清细菌内毒素、D-乳酸及二胺氧化酶变化的相关性研究

被引:4
作者
桂伟
机构
[1] 华中科技大学同济黄州医院普外科
关键词
重症肿瘤; 肠道功能评估; D-乳酸; 细菌内毒素; 二胺氧化酶;
D O I
暂无
中图分类号
R730.4 [肿瘤诊断学];
学科分类号
100214 [肿瘤学];
摘要
目的研究重症肿瘤患者肠道功能评估与血清D-乳酸(DLC)、细菌内毒素(BT)及二胺氧化酶(DAO)变化的相关性,为临床诊断及治疗提供参考。方法回顾性分析华中科技大学同济黄州医院ICU2015年12月至2017年12月收治的老年肿瘤患者234例为研究对象,根据是否合并胃肠功能障碍分组,合并胃肠功能障碍70例为研究组,发生率29.9%,另164例为对照组。所有受检者于入科24 h内进行急性生理与慢性健康评分(APACHEⅡ评分),并统计病死率。应用联检试剂盒(酶法)检测DLC、BT及DAO变化,并分析重症肿瘤患者APACHEⅡ评分与上述指标的相关性。结果研究组DLC、BT、DAO分别为(24.3±16.5)mg/L、(11.4±9.7)U/L、(16.5±22.6)U/L,均高于对照组的(11.7±12.4)mg/L、(9.3±10.2)U/L、(6. 3±9. 6) U/L,差异均有统计学意义(均P <0.05);Spearman相关分析显示,患者APACHEⅡ评分与DLC、BT及DAO均呈正相关(r=0. 53,P<0.05;r=0.45,P <0.05;r=0.43,P=0.01)。结论重症肿瘤胃肠功能障碍患者DLC、BT及DAO均明显升高,且与APACHEⅡ评分呈正相关,值得临床注意。
引用
收藏
相关论文
共 4 条
[1]
Acupuncture for Ischemic Stroke; Music for Anxiety in Mechanical Ventilation; Essential Fatty Acids for Depression; Mindfulness Meditation for Sleep in Older Adults; Tripterygium wilfordii for Rheumatoid Arthritis[J] Richard Glickman-Simon;Justin Steurich Explore: The Journal of Science and Healing 2016,
[2]
Gestational Diabetes Mellitus Is Associated With Changes in the Concentration and Bioactivity of Placenta-Derived Exosomes in Maternal Circulation Across Gestation[J] Emma Sweeney;Miharu Kobayashi;Paula Correa;Sherri Longo;Gregory Duncombe;Murray D Mitchell;Gregory E Rice;Sebastian E Illanes Diabetes 2016,
[3]
Alberta Stroke Program Early Computed Tomographic Scoring Performance in a Series of Patients Undergoing Computed Tomography and MRI: Reader Agreement; Modality Agreement; and Outcome Prediction[J] Ryan A. McTaggart;Tudor G. Jovin;Maarten G. Lansberg;Michael Mlynash;Mahesh V. Jayaraman;Omar A. Choudhri;Manabu Inoue;Michael P. Marks;Gregory W. Albers Stroke 2015,
[4]
Satisfaction With Activity and Participation and Its Relationships With Body Functions; Activities; or Environmental Factors in Stroke Patients[J] édouard Bouffioulx;Carlyne Arnould;Jean-Louis Thonnard Archives of Physical Medicine and Rehabilitation 2011,