椎间盘源性下腰痛的组织病理学变化

被引:15
作者
郭团茂
陈忠宁
王忠贵
机构
[1] 咸阳市中心医院骨二科
关键词
椎间盘源性下腰疼; 临床诊断; 敏感性; 特异性; MRI;
D O I
暂无
中图分类号
R681.5 [脊柱及背疾病];
学科分类号
100220 [骨科学];
摘要
背景:椎间盘源性下腰痛是一种椎间盘外周部基本保持完整,而内部各种病理(退变、终板损伤、炎症等)刺激椎间盘内疼痛感受器引起的功能丧失性下腰痛,并且不伴有根性症状,无神经或节段过度活动的放射学证据。目的:综述了椎间盘源性下腰痛病理变化、临床诊断的特异性、敏感性和安全性以及各种诊断方法存在的争议观点。方法:应用计算机检索中国期刊全文数据库、PubMed数据库、EMBASE数据库1970/2010有关椎间盘源性下腰痛诊断的文献,排除重复性研究。结果与结论:共保留42篇文献归纳总结。目前临床上根据椎间盘源性下腰痛的病理变化有多种诊断方法,包括物理检查的中心化趋势和骨震动测试,MRI上的黑间盘、高密度区、Modic改变,椎间盘超声检查,血清学中的高敏感性C-反应蛋白和椎间盘造影。其中腰椎间盘造影有较高的敏感性和特异性,是目前首选的诊断方法。
引用
收藏
页码:7366 / 7370
页数:5
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