低分子量肝素在治疗血栓性疾病中的应用

被引：39

作者：

盛爱珍

机构：

[1] 北京医院脑系科

来源：

国外医学(脑血管疾病分册) | 1997年 / 02期

关键词：

低分子量肝素; 治疗; 疗效; 耐受性;

D O I：

暂无

中图分类号：

R559 [其他血液病];

学科分类号：

100201 [内科学];

摘要：

近年来发现低分子量肝素在预防和治疗血栓性疾病时较普通肝素副作用少,作用较肯定,且使用方便。文章综述了低分子量肝素的成分、作用机制及在预防和治疗深静脉血栓形成、冠心病和缺血性脑血管病的资料,复习了其副作用和耐受性问题。但文献中治疗缺血性脑血管病的资料较少,需作进一步临床观察。

引用

页码：99 / 104

页数：6

共 7 条

[1]

Low-molecular-weight heparin during instability in coronary artery disease [J].

Wallentin, L ;

Ohlsson, J ;

Swahn, E ;

Karlsson, E ;

Lundin, L ;

Landgren, F ;

Saetre, H ;

Adren, B ;

Enghoff, E ;

Lundstrom, T ;

Hjalmarsson, A ;

Nordlander, R ;

Andren, B ;

Blomstrand, P ;

Venge, P ;

Siegbahn, A ;

Almroth, G ;

Johansson, C ;

Normark, A ;

Wiklund, K ;

Logander, E ;

Lindstrom, G ;

Svensson, E ;

Undeland, S ;

Neiger, K ;

Perers, G ;

Irving, P ;

Andersson, I ;

Hammarstrom, E ;

Bastani, H ;

Eng, E ;

Lundin, P ;

Rehnqvist, N ;

Ambrant, B ;

Oblack, P ;

Holmstrand, M ;

Ekdahl, S ;

Nyman, I ;

Pantzar, Y ;

Ahlberg, G ;

Hagstrom, L ;

Sundqvist, C ;

Pihl, E ;

Gustafsson, G ;

Larsson, L ;

Gustavsson, PE ;

Lofmark, R ;

Lundqvist, IB ;

Lundqvist, L ;

Angman, K .

LANCET, 1996, 347 (9001) :561-568

[2]

Low-molecular-weight heparin during pregnancy and delivery: Preliminary experience with 41 pregnancies [J].

Dulitzki, M ;

Pauzner, R ;

Langevitz, P ;

Pras, M ;

Many, A ;

Schiff, E .

OBSTETRICS AND GYNECOLOGY, 1996, 87 (03) :380-383

[3]

PROSPECTIVE, RANDOMIZED, PLACEBO-CONTROLLED, DOUBLE-BLIND, MULTICENTER STUDY OF EXERCISE WITH ENOXAPARIN PRETREATMENT FOR STABLE-EFFORT ANGINA [J].

FUJITA, M ;

SASAYAMA, S ;

KATO, K ;

TAKAORI, S ;

ONODERA, K ;

MIKUNIYA, A ;

AIZAWA, T ;

KIRIGAYA, H ;

SUZUKI, S ;

KITAHARA, K ;

OGAWA, T ;

NAKAGOMI, A ;

NAKAMURA, Y ;

OGAWA, S ;

AKAISHI, M ;

HOSODA, S ;

IWADE, K ;

MOTOMIYA, T ;

TEJIMA, T ;

JIMBO, M ;

TAKEDA, R ;

SHIMIZU, M ;

TAKEGOSHI, R ;

KANEMITSU, S ;

EJIRI, M ;

NAKAMURA, T ;

LEE, JD ;

TAKAHASHI, M ;

NAKANO, T ;

YAMAKADO, T ;

KINOSHITA, M ;

YAMADA, T ;

KODAMA, K ;

HIRAYAMA, A ;

SATO, H ;

YOSHIMURA, M .

AMERICAN HEART JOURNAL, 1995, 129 (03) :535-541

[4]

LOW-MOLECULAR-WEIGHT HEPARIN VERSUS REGULAR HEPARIN OR ASPIRIN IN THE TREATMENT OF UNSTABLE ANGINA AND SILENT ISCHEMIA [J].

GURFINKEL, EP ;

MANOS, EJ ;

MEJAIL, RI ;

CERDA, MA ;

DURONTO, EA ;

GARCIA, CN ;

DAROCA, AM ;

MAUTNER, B .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 1995, 26 (02) :313-318

[5]

COMPARISON OF EFFICACY AND SAFETY OF LOW-MOLECULAR-WEIGHT HEPARINS AND UNFRACTIONATED HEPARIN IN INITIAL TREATMENT OF DEEP VENOUS THROMBOSIS - A METAANALYSIS [J].

LEIZOROVICZ, A ;

SIMONNEAU, G ;

DECOUSUS, H ;

BOISSEL, JP .

BMJ-BRITISH MEDICAL JOURNAL, 1994, 309 (6950) :299-304

[6]

PILOT-STUDY OF LOW-MOLECULAR-WEIGHT HEPARIN IN THE TREATMENT OF ACUTE ISCHEMIC STROKE [J].

KAY, R ;

WONG, KS ;

WOO, J .

STROKE, 1994, 25 (03) :684-685

[7]

A DOSE ESCALATION STUDY OF ORG-10172 (LOW-MOLECULAR WEIGHT HEPARINOID) IN STROKE [J].

BILLER, J ;

MASSEY, EW ;

MARLER, JR ;

ADAMS, HP ;

DAVIS, JN ;

BRUNO, A ;

HENRIKSEN, RA ;

LINHARDT, RJ ;

GOLDSTEIN, LB ;

ALBERTS, M ;

KISKER, CT ;

TOFFOL, GJ ;

GREENBERG, CS ;

BANWART, KJ ;

BERTELS, C ;

BECK, DW ;

WALKER, M ;

MAGNANI, HN .

NEUROLOGY, 1989, 39 (02) :262-265

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