间充质干细胞培养与分化诱导的特点及机制

被引:7
作者
赵林 [1 ]
申延清 [1 ]
荣春 [1 ]
周岩冰 [2 ]
夏长所 [3 ]
机构
[1] 青岛大学医学院附属医院手术室
[2] 青岛大学医学院附属医院普外科
[3] 青岛大学医学院附属医院骨科
关键词
间充质干细胞; 培养; 分化; 诱导; 综述文献;
D O I
暂无
中图分类号
R329 [人体组织学];
学科分类号
100107 [人体解剖与组织胚胎学(人体解剖学、组织与胚胎学)];
摘要
背景:间充质干细胞是目前备受关注的一类具有多向分化潜能的成体干细胞。目的:对间充质干细胞分离、鉴别、生物学特性及应用前景做一综述。方法:应用计算机检索Medline数据库(1996-01/2010-03),以"mese nchymal stem cell"为检索词;同时检索CNKI数据库(1979/2010-02),以"间充质干细胞、培养、分化"为检索词。结果与结论:共收集400篇关于间充质干细胞分离、培养、鉴定和分化的文献,中文86篇,英文314篇。排除发表时间较早、重复及类似研究,纳入36篇符合标准的文献。发现间充质干细胞分离、培养、鉴定虽然有多种方法,但还没有统一的标准,细胞分化诱导的机制仍不清楚,应用也存在诸多问题。
引用
收藏
页码:7551 / 7554
页数:4
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