凝血酶的神经保护作用

被引：3

作者：

韩国玲

姜亚军

机构：

[1] 东南大学附属中大医院神经内科

[2] 江苏省中医院脑病中心南京

[3] 南京

来源：

国外医学(脑血管疾病分册) | 2004年 / 03期

关键词：

凝血酶; 凝血酶受体; 凝血酶预处理; 神经保护; 信号转导;

D O I：

暂无

中图分类号：

R96 [药理学];

学科分类号：

100602 ; 100706 ;

摘要：

凝血酶在脑血管病中的作用日益受到重视。已有研究证实,凝血酶具有双向作用,小剂量可产生神经保护作用,大剂量则具有细胞毒性作用。小剂量凝血酶预处理可减轻大剂量凝血酶对神经细胞的毒性作用,其作用机制与MAPK信号转导途径、HSP表达等有关。

引用

页码：234 / 236

页数：3

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