rtPA动脉内溶栓在急性脑梗死治疗中的临床应用

被引:13
作者
李海林
耿晓增
傅震
机构
[1] 南京医科大学第一附属医院神经外科
关键词
重组组织型纤溶酶原激活物; 卒中; 溶栓疗法;
D O I
暂无
中图分类号
R743.33 [脑栓塞];
学科分类号
摘要
动脉内溶栓治疗急性脑梗死有明显的疗效,rtPA是一种新型溶栓药物,文章阐述了该药物的溶栓原理、用量、方法以及动脉内给药的优越性和溶栓并发症问题。
引用
收藏
页码:175 / 177
页数:3
相关论文
共 7 条
  • [1] Intra-arterial third-generation recombinant tissue plasminogen activator (reteplase) for acute ischemic stroke
    Qureshi, AI
    Ali, Z
    Suri, MFK
    Kim, SH
    Shatla, AA
    Ringer, AJ
    Lopes, DK
    Guterman, LR
    Hopkins, LN
    [J]. NEUROSURGERY, 2001, 49 (01) : 41 - 48
  • [2] Acute Interventions for Ischemic Stroke: Present Status and Future Directions[J] . Adnan I. Qureshi,Andrew J. Ringer,M. Fareed K. Suri,Lee R. Guterman,L. Nelson Hopkins.The Journal of Endovascular Therapy . 2000 (5)
  • [3] Third-generation thrombolytic drugs
    Verstraete, M
    [J]. AMERICAN JOURNAL OF MEDICINE, 2000, 109 (01) : 52 - 58
  • [4] Combined Intravenous and Intra-Arterial r-TPA Versus Intra-Arterial Therapy of Acute Ischemic Stroke: Emergency Management of Stroke (EMS) Bridging Trial[J] . Christopher A. Lewandowski,Michael Frankel,Thomas A. Tomsick,Joseph Broderick,James Frey,Wayne Clark,Sidney Starkman,James Grotta,Judith Spilker,Jane Khoury,Thomas Brott.Stroke . 1999 (12)
  • [5] Randomised double-blind placebo-controlled trial of thrombolytic therapy with intravenous alteplase in acute ischaemic stroke (ECASS II)
    Hacke, W
    Kaste, M
    Fieschi, C
    von Kummer, R
    Davalos, A
    Meier, D
    Larrue, V
    Bluhmki, E
    Davis, S
    Donnan, G
    Schneider, D
    Diez-Tejedor, E
    Trouillas, P
    [J]. LANCET, 1998, 352 (9136) : 1245 - 1251
  • [6] The effect of intravenous thrombolytic therapy on left ventricular function: a report on tissue-type plasminogen activator and streptokinase from the Thrombolysis in Myocardial Infarction (TIMI Phase I) Trial*[J] . FLORENCE H. SHEEHAN,EUGENE BRAUNWALD,PAUL CANNER,HAROLD T. DODGE,JOEL GORE,PEARL VAN NATRA,EUGENE R. PASSAMANI,DAVD 0. WILLIAMS,BARRY ZARET.Circulation . 1987 (4)
  • [7] Intravenous tissue-type plasminogen activator for treatment of acute stroke: the Standard Treatment with Alteplase to Reverse Stroke (STARS ) study .2 Albers GW,Bates VE,Clark WM,et al. JAMA . 2000