Volumetric MRI Analysis of the Amygdala and Hippocampus in Subjects with Major Depression

被引：1

作者：

夏军

陈军

周义成

张景峰

杨波

夏黎明

王承缘

机构：

[1] DepartmentofRadiology,TongjiHospital,TongjiMedicalCollege,HuazhongUniversityofScienceandTechnology,Wuhan,China,DepartmentofRadiology,RenminHospital,WuhanUniversity,Wuhan,China,DepartmentofRadiology,TongjiHospital,TongjiMedicalCollege,HuazhongUniversityofSc

来源：

华中科技大学学报(医学英德文版) | 2004年 / 05期

关键词：

D O I：

暂无

中图分类号：

R445.2 [核磁共振成像];

学科分类号：

100231 [临床病理学];

摘要：

In order to explore the MRI volume of the amygdala and hippocampus in patients with major depression, quantitative MRI of the amygdala and hippocampus were studied in 22 patients with major depression and compared with 13 age-matched controls. The results showed that both groups exhibited similar significant hippocampal asymmetry (left smaller than right). The volume of the bilateral hippocampus was significantly smaller in the major depression group than that in control group. The patients had significant asymmetry of the amygdalar volumes (right smaller than left). No correlation was found between hippocampal volume abnormalities and ill duration. It was concluded that the hippocampus and amygdala within limbic-cortical networks may play a crucial role in the pathogenesis of major depression.

引用

页码：500 / 502+506 +506

页数：4