体脂对DXA骨密度测量结果及骨质疏松诊断的影响

被引：10

作者：

伍媛 ^{[1
]}

邓小戈 ^{[2
]}

机构：

[1] 湖南省人民医院老干高知科

[2] 中南大学湘雅二医院代谢内分泌研究所

来源：

国际病理科学与临床杂志 | 2009年 / 29卷 / 03期

关键词：

骨密度; 脂肪; 双能X线测量; 骨质疏松;

D O I：

暂无

中图分类号：

R580 [];

学科分类号：

摘要：

随着社会老龄化和生活水平提高,制约老年人健康长寿的骨质疏松症受到越来越多的重视。双能X线吸收测量法(dual energy X-ray absorptiometer,DXA)测量骨密度是诊断骨质疏松的金标准,但它的精确性受身体脂肪含量的影响。体脂可以干扰DXA测量骨密度的结果,这可能会导致体脂分布改变显著者(如绝经后体脂分布变化较大的女性)骨质疏松诊断的偏倚,造成此类人群骨质疏松时误诊或漏诊的发生。本文就脂肪对骨密度测量结果及骨质疏松诊断的影响作一综述。

引用

页码：272 / 276

页数：5

共 29 条

[1]

Bone mineral density in prepubertal obese and control children: relation to body weight, lean mass, and fat mass [J].

Rocher, Emilie ;

Chappard, Christine ;

Jaffre, Christelle ;

Benhamou, Claude-Laurent ;

Courteix, Daniel .

JOURNAL OF BONE AND MINERAL METABOLISM, 2008, 26 (01) :73-78

[2]

Relationships between fat and bone [J].

Reid, I. R. .

OSTEOPOROSIS INTERNATIONAL, 2008, 19 (05) :595-606

[3]

A cohort study of the effect of endogenous estrogen on spine fracture risk and bone structure in elderly women and an assessment of its diagnostic usefulness [J].

Prince, R. L. ;

Dick, I. M. ;

Beilby, J. ;

Dhaliwal, S. S. ;

Devine, A. .

BONE, 2007, 41 (01) :33-38

[4]

Population-based reference values for bone mineral density in young men [J].

Hoiberg, M. ;

Nielsen, T. L. ;

Wraae, K. ;

Abrahamsen, B. ;

Hagen, C. ;

Andersen, M. ;

Brixen, K. .

OSTEOPOROSIS INTERNATIONAL, 2007, 18 (11) :1507-1514

[5]

Racial differences in the association of subcutaneous and visceral fat on bone mineral content in prepubertal children [J].

Afghani, A. ;

Goran, M. I. .

CALCIFIED TISSUE INTERNATIONAL, 2006, 79 (06) :383-388

[6]

Overweight and obesity in China [J].

Wu, Yangfeng .

BMJ-BRITISH MEDICAL JOURNAL, 2006, 333 (7564) :362-363

[7]

Simulated change in body fatness affects hologic QDR 4500A whole body and central DXA bone measures [J].

Evans, Ellen M. ;

Mojtahedi, Mina C. ;

Kessinger, Renee B. ;

Misic, Mark M. .

JOURNAL OF CLINICAL DENSITOMETRY, 2006, 9 (03) :315-322

[8]

Association of Body Composition and Physical Activity with Proximal Femur Geometry in Middle-Aged and Elderly Afro-Caribbean Men:.[J].L.M. Semanick;T.J. Beck;J.A. Cauley;V.W. Wheeler;A.L. Patrick;C.H. Bunker;J.M. Zmuda.Calcified Tissue International.2005, 3

[9]

Differences in peak bone mass in women of European and South Asian origin can be explained by differences in body size [J].