急性肾损伤的诊断:肌酐还是尿量?

被引：12

作者：

罗旭颖 ^{[1
]}

周建新 ^{[1
]}

席修明 ^{[2
]}

机构：

[1] 首都医科大学附属北京天坛医院重症医学科

[2] 首都医科大学附属复兴医院重症医学科

来源：

中华重症医学电子杂志 | 2017年 / 3卷 / 01期

关键词：

急性肾损伤; 肌酸酐; 肾小球滤过率; 死亡率; 诊断; 尿量;

D O I：

暂无

中图分类号：

R692 [肾疾病];

学科分类号：

摘要：

急性肾损伤(acute kidney injury,AKI)是临床常见疾病,在危重症患者中发病率更高,导致患者病死率增加。近年来普遍应用的AKI诊断标准,均以血清肌酐(Scr)及尿量改变为依据,进行诊断及分级。但是,二者在临床应用中仍存在争议,如基础肌酐值的确定、尿量减少阈值及持续时间的判断,以及液体平衡对二者的影响等。而Scr与尿量联合应用,虽可提高AKI的诊断敏感度,有助于筛查高危AKI患者,但却降低了AKI的诊断特异度,可能误诊AKI;并且二者对住院病死率的预测能力,亦尚无确切结论。

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页码：9 / 13

页数：5

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