脂联素——一种新的抗炎因子

被引：20

作者：

陈懿建 ^{[1
]}

万通 ^{[1
]}

陈方平 ^{[2
]}

机构：

[1] 赣南医学院第一附属医院血液科

[2] 中南大学湘雅医院血液科

来源：

国际病理科学与临床杂志 | 2009年 / 29卷 / 01期

关键词：

Adp; Adp受体; 抗炎因子; 动脉粥样硬化;

D O I：

暂无

中图分类号：

R341 [];

学科分类号：

摘要：

动脉粥样硬化是一种以慢性轻度炎症为特征的疾病。脂联素(ad iponectin,Adp)作为脂肪组织分泌的一种脂肪细胞因子具有改善胰岛素敏感性、保护血管内皮功能、抗动脉粥样硬化及抗炎作用。多项临床研究表明血浆Adp水平与多种炎症标志物呈负相关。在多种细胞中Adp能减轻炎症刺激物引起的炎症反应。Adp的抗炎特性可能是其对心血管和代谢性疾病如动脉粥样硬化及胰岛素抵抗起有利作用的主要原因。

引用

页码：86 / 92

页数：7

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