糖尿病脑病

被引:19
作者
孙海鸥
殷玉华
姬秋和
机构
[1] 第四军医大学西京医院内分泌科
[2] 第四军医大学西京医院内分泌科 西安
[3] 西安
关键词
糖尿病神经病变; 糖尿病脑病; 认知功能; 钙离子稳态;
D O I
暂无
中图分类号
R747.9 [并发神经病];
学科分类号
1002 ;
摘要
糖尿病脑病指的是糖尿病引起的认知障碍和大脑的神经生理及结构的改变。文中讨论了糖尿病脑病的临床特征及神经生理(海马趾的突触可塑性)改变。糖尿病脑病的发病机制比较复杂,包括脑血管改变、氧化应激、非酶性蛋白糖基化、胰岛素副作用及钙稳态的破坏等,最终导致神经元的损害,继而认知功能障碍。其诊断、治疗及预防目前还没有达成一致的观点。
引用
收藏
页码:79 / 81
页数:3
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