溃疡性结肠炎相关性结直肠癌的危险因素及预防

被引：23

作者：

刘斌

阳惠湘

机构：

[1] 中南大学湘雅医院消化内科

来源：

国际病理科学与临床杂志 | 2012年 / 32卷 / 03期

关键词：

溃疡性结肠炎; 结直肠癌; 不典型增生; 危险因素; 化学预防;

D O I：

暂无

中图分类号：

R574.62 [结肠疾病];

学科分类号：

100201 [内科学];

摘要：

溃疡性结肠炎是一种直肠及结肠的慢性非特异性炎症性疾病,临床以反复发作的腹泻、腹痛和黏液脓血便为特征。溃疡性结肠炎相关性结直肠癌是溃疡性结肠炎严重的并发症及重要死亡原因,其危险因素包括病程、病变范围、原发性硬化性胆管炎、结直肠癌家族史、发病年龄及炎症严重程度等。不典型增生是溃疡性结肠炎相关性结直肠癌发生的重要环节,早期发现不典型增生,积极化学预防是预防溃疡性结肠炎癌变的关键。

引用

页码：244 / 252

页数：9

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