兴奋性氨基酸与疼痛中枢敏感化

被引:14
作者
温来友
机构
[1] 徐州医学院江苏省麻醉学重点实验室()
关键词
兴奋性氨基酸; 受体; 疼痛; 脊髓; 中枢敏感化;
D O I
暂无
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
兴奋性氨基酸是以谷氨酸及天冬氨酸为代表的司理兴奋性神经传导的神经递质,通过相应的受体参与体内各种信号传递和调节神经元的兴奋性。大量研究证实多种病理性疼痛的发生与脊髓背角的中枢敏感化存在密切关系,体内有多种介质参与疼痛中枢敏感化的形成,其中兴奋性氨基酸在疼痛中枢敏感化的形成过程中起重要作用。
引用
收藏
页码:372 / 375
页数:4
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