非酒精性脂肪肝及其与代谢综合征关系的研究进展

被引：14

作者：

楚蓝

戴红

机构：

[1] 武汉科技大学医学院预防医学系

来源：

国外医学(卫生学分册) | 2009年 / 36卷 / 06期

关键词：

非酒精性脂肪肝; 代谢综合征; 肥胖; 胰岛素抵抗;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍]; R589 [代谢病];

学科分类号：

1002 ; 100201 ;

摘要：

非酒精性脂肪肝是一组包括从单纯性脂肪肝到非酒精性脂肪性肝炎,以致最终发展为肝硬化及肝细胞癌的慢性肝脏疾病。非酒精性脂肪肝通常与代谢综合征的各组分密切相关,也是代谢综合征的肝病表现,其致病机制涉及胰岛素抵抗、氧化应激、细胞凋亡和脂肪因子等多重打击过程。不合理饮食是导致非酒精性脂肪肝发生的主要原因,膳食效应通过影响激素、转录因子以及脂质代谢途径来影响全身代谢及其调控。

引用

页码：383 / 385

页数：3

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