有机磷农药所致神经发育毒性及机制

被引:5
作者
赵玲玲 [1 ]
张洁 [2 ]
刘罗慧 [1 ]
机构
[1] 中南大学湘雅三医院儿科
[2] 中南大学湘雅二医院神经内科
关键词
有机磷农药; 发育神经毒性; 机制;
D O I
暂无
中图分类号
R114 [卫生毒理];
学科分类号
100405 ;
摘要
有机磷农药(organophosphorus pesticides,OPs)产生的毒性除了全身毒性症状外,还具有神经发育毒性,胚胎期和出生后有机磷农药暴露能对快速生长发育中的胎儿和婴幼儿健康造成潜在的危害,并可能持续存在,在短期或远期内诱发某些神经精神类疾病。除胆碱酯酶抑制途径外,其他非胆碱酯酶途径也参与了其神经发育毒性作用,虽然具体机制还未明确,但已发现涉及细胞信号途径。
引用
收藏
页码:72 / 76
页数:5
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