ER通路信号传导与选择性雌激素受体调节剂耐药机制研究

被引:2
作者
徐迎春
张凤春
林玉梅
机构
[1] 上海第二医科大学附属仁济医院肿瘤科
关键词
乳腺肿瘤; 雌激素拮抗剂; 药物耐受性;
D O I
暂无
中图分类号
R737.9 [乳腺肿瘤];
学科分类号
100214 ;
摘要
内分泌治疗是乳腺癌综合治疗中的重要措施之一 ,此疗法面临的最大难题是原发性、继发性耐药 ,其确切机制尚不清楚。雌激素受体 (ER)信号传导途径及各辅助因子的分子调控是近年来研究的重点 ,现综述有关研究进展 ,以期为临床选择性ER调节剂 (SERM)耐药病例的治疗及耐药逆转提供帮助
引用
收藏
页码:163 / 166
页数:4
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