弥散张量成像在脊髓型颈椎病中的应用进展

被引：5

作者：

王琨 ^{[1
]}

郝强 ^{[2
]}

沈洪兴 ^{[1
]}

机构：

[1] 第二军医大学长海医院骨科

[2] 第二军医大学长海医院影像科

来源：

第二军医大学学报 | 2014年 / 35卷 / 07期

关键词：

脊髓型颈椎病; 磁共振成像; 弥散张量成像; 表观弥散系数; 各向异性分数; 纤维束示踪成像;

D O I：

暂无

中图分类号：

R445.2 [核磁共振成像]; R681.55 [];

学科分类号：

100231 [临床病理学];

摘要：

脊髓型颈椎病(CSM)是老年人群中的常见疾病,由颈椎退变导致脊髓慢性受压所引起。磁共振成像(MRI)可显示椎管是否狭窄、脊髓受压的程度和信号的改变,但对脊髓轻度变性和微观结构的改变敏感性较低且不能定量分析。弥散张量成像(DTI)是一种可以评价神经纤维细胞内外水分子弥散特征的MRI新技术,评价参数包括表观弥散系数(ADC)和各向异性分数(FA),并可利用纤维束示踪成像(DTT)清晰地显示出神经纤维束的形态,是目前唯一可无创显示活体神经纤维束的方法。研究表明,DTI参数对CSM的早期诊断、神经功能评估和预后判断较常规MRI更加敏感,DTT可清晰显示脊髓纤维束形态和连续性的改变,也可准确评估神经功能并预测患者手术预后,但脊髓DTI成像仍有许多干扰因素,脊髓DTI参数如何测量和分析尚无统一标准,并且DTT能否完全反映脊髓真实病理状态,有待进一步研究。本文就脊髓DTI成像技术发展和DTI在CSM中的研究进展作一综述。

引用

页码：780 / 785

页数：6

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