孕激素在绝经后骨质疏松中的作用

被引:21
作者
梁敏
机构
[1] 中南大学湘雅二院代谢内分泌研究所湖南长沙
基金
“九五”攻关项目;
关键词
孕激素; 骨质疏松; 成骨细胞;
D O I
暂无
中图分类号
R58 [内分泌腺疾病及代谢病];
学科分类号
100201 [内科学];
摘要
动物实验和临床研究均证实孕激素可治疗绝经后骨质疏松,并与雌激素有协同作用。孕激素通过成骨细胞上的孕激素受体影响成骨细胞的增殖和分化,加速骨形成;同时竞争糖皮质激素受体及刺激降钙素的分泌,影响骨吸收。
引用
收藏
页码:136 / 138
页数:3
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