创伤性颅脑损伤后的睡眠障碍

被引：10

作者：

盛平

侯立军

董艳

机构：

[1] 第二军医大学长征医院神经外科

来源：

第二军医大学学报 | 2012年 / 33卷 / 11期

基金：

教育部留学回国人员科研启动基金;

关键词：

睡眠障碍; 颅脑损伤; 昼夜节律;

D O I：

暂无

中图分类号：

R651.1 [颅脑];

学科分类号：

1002 ; 100210 ;

摘要：

睡眠障碍是颅脑损伤(traumatic brain injury,TBI)后最常见的伴随症状,超过50%的TBI患者存在不同程度的失眠、嗜睡、昼夜节律失调等表现。长期的睡眠障碍可严重影响患者的精神状态、认知功能及脑损伤的修复,且能增加交通事故等TBI的风险因素。下丘脑-垂体-靶腺轴功能紊乱所引起的一系列神经内分泌异常可能是睡眠障碍发生的主要原因。目前对TBI后各种类型睡眠障碍的诊断尚无统一标准,治疗仍以催眠类药物为主、行为干预为辅,然而催眠类药物对TBI后睡眠障碍的疗效及不良反应尚欠缺全面的评估。不同类型TBI后睡眠障碍的各种表现形式及其机制研究能指导临床治疗,个体化治疗的实现也将对促进TBI后睡眠障碍患者康复起到积极作用。

引用

页码：1253 / 1256

页数：4

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