The MetaCyc database of metabolic pathways and enzymes

被引：626

作者：

Caspi, Ron ^{[1
]}

Billington, Richard ^{[1
]}

Fulcher, Carol A. ^{[1
]}

Keseler, Ingrid M. ^{[1
]}

Kothari, Anamika ^{[1
]}

Krummenacker, Markus ^{[1
]}

Latendresse, Mario ^{[1
]}

Midford, Peter E. ^{[1
]}

Ong, Quang ^{[1
]}

Ong, Wai Kit ^{[1
]}

Paley, Suzanne ^{[1
]}

Subhraveti, Pallavi ^{[1
]}

Karp, Peter D. ^{[1
]}

机构：

[1] SRI Int, 333 Ravenswood, Menlo Pk, CA 94025 USA

来源：

NUCLEIC ACIDS RESEARCH | 2018年 / 46卷 / D1期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1093/nar/gkx935

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

MetaCyc (https://MetaCyc.org) is a comprehensive reference database of metabolic pathways and enzymes from all domains of life. It contains more than 2570 pathways derived from > 54 000 publications, making it the largest curated collection of metabolic pathways. The data in MetaCyc is strictly evidence-based and richly curated, resulting in an encyclopedic reference tool for metabolism. MetaCyc is also used as a knowledge base for generating thousands of organism-specific Pathway/Genome Databases (PGDBs), which are available in the Bio-Cyc (https://BioCyc.org) and other PGDB collections. This article provides an update on the developments in MetaCyc during the past two years, including the expansion of data and addition of new features.

引用

页码：D633 / D639

页数：7

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