Predictive Value of the HAS-BLED Score for the Risk of Recurrent Intracranial Hemorrhage After First Spontaneous Intracranial Hemorrhage

被引：21

作者：

Chan, Koon-Ho ^{[1
]}

Leung, Gilberto Ka-Kit ^{[2
]}

Lau, Kui-Kai ^{[1
]}

Liu, Shasha ^{[3
]}

Lui, Wai-Man ^{[2
]}

Lau, Chu Pak ^{[3
]}

Tse, Hung-Fat ^{[3
]}

Pu, Jenny Kan-Suen ^{[2
]}

Siu, Chung-Wah ^{[3
]}

机构：

[1] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Div Neurol, Hong Kong, Hong Kong, Peoples R China

[2] Univ Hong Kong, Li Ka Shing Fac Med, Dept Surg, Div Neurosurg, Hong Kong, Hong Kong, Peoples R China

[3] Univ Hong Kong, Li Ka Shing Fac Med, Dept Med, Div Cardiol, Hong Kong, Hong Kong, Peoples R China

来源：

WORLD NEUROSURGERY | 2014年 / 82卷 / 1-2期

关键词：

HAS-BLED score; Intracranial hemorrhage; Recurrence; ATRIAL-FIBRILLATION; ISCHEMIC-STROKE; CASE-FATALITY; RECOVERY;

D O I：

10.1016/j.wneu.2013.02.070

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

BACKGROUND: Patients who survive intracranial hemorrhage (ICH) are at high risk of recurrence. The Hypertension, Abnormal Renal/Liver Function, Stroke, Bleeding History or Predisposition, Labile INR, Elderly (Age >65 years), Drugs/Alcohol Concomitantly (HAS-BLED) score has recently been developed to assess bleeding risk. METHODS: This observational study was aimed to investigate the prognostic performance of the HAS-BLED score in predicting recurrent ICH. Consecutive patients (434) with a first spontaneous ICH who were not prescribed antiplatelet or anticoagulation therapy (59.8 +/- 15.3 years; men, 62.3%) were recruited. RESULTS: Most patients (71.6%) had a HAS-BLED score of >1. After a follow-up of 52.7 months, there were 42 ICH recurrences (2.25 per 100 patient-years). The risk of ICH recurrence increased with HAS-BLED score. Specifically, the risk of ICH recurrence with HAS-BLED score of 1, 2, 3, and 4 were 1.37, 2.38, 3.39, and 2.90 per 100 patient-years, respectively. The sensitivity and specificity of HAS-BLED was 79.1% and 29.2%, respectively, with C-statistic of 0.54 (0.50-0.59). CONCLUSION: This study provided data on the risk of ICH recurrence stratified using the HAS-BLED score in patients after an ICH.

引用

页码：E219 / E223

页数：5

共 17 条

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