Development of biomimetic nano-hydroxyapatite/poly(hexamethylene adipamide) composites

被引：384

作者：

Wang, Xuejiang ^{[1
]}

Li, Yubao ^{[1
]}

Wei, Jie ^{[1
]}

De Groot, Klass ^{[2
]}

机构：

[1] Institute of Materials Science and Technology, Sichuan University, 610064 Chengdu, China

[2] Biomaterials Reasearch Group, Faculty of Medicine, University of Leiden, Prof. Bronkhorstlaan 10, 3723 MB Blithoven, Netherlands

来源：

Biomaterials | 2002年 / 23卷 / 24期

关键词：

Biomimetic materials - Biosynthesis - Bone - Crystal structure - Hydroxyapatite;

D O I：

10.1016/S0142-9612(02)00229-6

中图分类号：

学科分类号：

摘要：

In this study, acicular nano-hydroxyapatite (n-HA) was used to make a new biomimetic composite with polyamide (poly hexamethylene adipamide) by a unique technique. The physical and chemical characteristics of the composites were tested. It was found that these synthesized n-HA crystals were similar to bone apatite in size, phase composition and crystal structure. The biomimetic n-HA crystals were uniformly distributed in the polymer matrix and its content can reach 65%, close to that in natural bone. Chemical binding between inorganic n-HA and polyamide was investigated and discussed. The mechanical properties of the composites were found to match well with those of natural bone. © 2002 Elsevier Science Ltd. All rights reserved.

引用

页码：4787 / 4791