Evolving strategies for protein synthesis converge on native chemical ligation

被引:101
作者
Department of Chemistry, University College London, Christopher Ingold Laboratories, 20 Gordon Street, London WC1H 0AJ, United Kingdom [1 ]
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来源
Angew. Chem. Int. Ed. | 2006年 / 46卷 / 7668-7672期
关键词
Molecular structure - Polypeptides - Proteins;
D O I
10.1002/anie.200602945
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摘要
(Figure Presented) Build a bridge: Although used widely, certain limitations of popular protein assembly strategies such as native chemical ligation (NCL) have persisted. This highlight presents the results of recent reports that tackle these limitations (see picture). Aux = auxiliary. © 2006 Wiley-VCH Verlag GmbH & Co. KGaA.
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