The paper evaluates the efficiency of extracorporeal life support (ECLS) in the setting of adult cardiorespiratory failure. Between 1988 and 1993, 65 moribund patients with respiratory and cardiac failures were supported with ECLS. Survival data are summarized as follows: pneumonia, 56%; adult respiratory distress syndrome, 58%; airway support, 100%; and cardiac support, 29%. Data from patients with respiratory failure were compared in an attempt to define prognostic indicators of improved survival. It is concluded that ECLS can be a life saving modality for the management of severe adult cardiorespiratory failure.