An interactive online computer system has been developed to process data collected during stereotaxic neurosurgical procedures, in order in facilitate more accurate localization of subcortical target sites. Responses evoked by electrical stimulation during thalamotomies are pictorially depicted on a template representative of the thalamic section being operated upon. This enables comparison of the evoked physiological responses with the accepted somato-topographic architecture of the thalamic area by visual inspection. New computer techniques are presented which minimize surgical complications due to the variability in brain dimensions between patients, and correct for errors due to misalignment of the stereotaxic apparatus.