VALPROIC ACID AND PLASMA-LEVELS OF PHENYTOIN

被引：34

作者：

BRUNI, J

WILDER, BJ

WILLMORE, LJ

BARBOUR, B

机构：

[1] VET ADM HOSP, MED CTR, NEUROL SERV 127, GAINESVILLE, FL 32602 USA

[2] UNIV FLORIDA, COLL MED, DEPT NEUROL, GAINESVILLE, FL 32611 USA

来源：

NEUROLOGY | 1979年 / 29卷 / 06期

关键词：

D O I：

10.1212/WNL.29.6.904

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Seizure patients (8) were treated concurrently with a constant dose of the anticonvulsants phenytoin and valproic acid for 1 yr. During initial therapy with valproic acid total plasma phenytoin levels decreased. The interaction was transient and was not seen at the end of 1 yr. Total plasma phenytoin levels returned to pre-valproic-acid levels in 7 patients.

引用

页码：904 / 905

页数：2

共 13 条

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