SYNTHESIS OF L-2-OXOTHIAZOLIDINE-4-CARBOXYLIC ACID

被引:14
作者
BOETTCHER, B
MEISTER, A
机构
关键词
D O I
10.1016/0003-2697(84)90837-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
An improved synthesis of L-2-oxothiazolidine-4-carboxylic acid is described. The new procedure, which leads to excellent yields of product, does not require the use of phosgene. The new method is thus less hazardous than the original one, and is readily adaptable to the preparation of 35S-labeled product. [This compound can be used as a cysteine delivery system to promote glutathione synthesis for protection against toxicity and as a component of amino acid mixtures for diets].
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页码:449 / 450
页数:2
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