MICROMETHOD FOR THE EMERGENCY ESTIMATION OF PLASMA PARACETAMOL CONCENTRATION USING HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：16

作者：

BUCHANAN, T

ADRIAENSSENS, P

STEWART, MJ

机构：

[1] UNIV EDINBURGH, DEPT CLIN CHEM, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

[2] UNIV EDINBURGH, DEPT CLIN PHYSIOL, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

[3] UNIV EDINBURGH, DEPT EXTRATERR PHYS, EDINBURGH EH3 9YW, MIDLOTHIAN, SCOTLAND

来源：

CLINICA CHIMICA ACTA | 1979年 / 99卷 / 02期

关键词：

D O I：

10.1016/0009-8981(79)90039-1

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

A method was developed for the emergency estimation of the antipyretic analgesic, paracetamol, using high performance liquid chromatography. The sample required is 100 .mu.l of human plasma. The use of a microcentrifuge reduces the total time for the estimation to 5 min from the receipt of the blood specimen. The method was compared with a standard UV method.

引用

页码：161 / 165

页数：5

共 11 条

[1] ADRIAENSSENS PI, 1978, J PHARM PHARMACOL, V6, P87
[2] BLAIR D, 1977, CLIN CHEM, V23, P743
[3] GIBSON PF, 1972, LANCET, V2, P607
[4] GLYNN JP, 1975, LANCET, V1, P1147
[5] GOTELLI GR, 1977, CLIN CHEM, V23, P957
[6] HORVITZ RA, 1977, CLIN CHEM, V23, P1596
[7] DETERMINATION OF ACETAMINOPHEN IN PHARMACEUTICAL PREPARATIONS AND BODY-FLUIDS BY HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY WITH ELECTROCHEMICAL DETECTION
RIGGIN, RM
SCHMIDT, AL
KISSINGER, PT
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1975, 64 (04) : 680 - 683
[8] ROUTH JI, 1968, CLIN CHEM, V14, P882
[9] STEWART MJ, ANN CLIN BIOCH
[10] REVIEW OF METHODS FOR PLASMA PARACETAMOL ESTIMATION
WIENER, K
[J]. ANNALS OF CLINICAL BIOCHEMISTRY, 1978, 15 (JUL) : 187 - 196

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