FINE-STRUCTURE OF SUB-CORTICAL NEUROFIBRILLARY TANGLES IN PROGRESSIVE SUPRANUCLEAR PALSY

被引：57

作者：

BUGIANI, O

MANCARDI, GL

BRUSA, A

EDERLI, A

机构：

[1] UNIV GENOA, NEUROL CLIN, I-16132 GENOA, ITALY

[2] OSPED GALLIERA, GENOVA, ITALY

[3] OSPED SAN FILIPPO, ROMA, ITALY

来源：

ACTA NEUROPATHOLOGICA | 1979年 / 45卷 / 02期

关键词：

Electron microscopy; Neurofibrillary tangles; Progressive supranuclear palsy; Straight filaments; Twisted tubules;

D O I：

10.1007/BF00691893

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

The fine structure of subcortical neurofibrillary tangles was investigated in pallidum, substantia nigra, periaqueductal gray, pontine reticular gray and dentate nucleus of 5 autopsy cases of progressive supranuclear palsy. Only tangles due to straight 150 .ANG. wide filaments were detected. These findings, obtained from a large series of cases and areas examined, confirm previous observations on the fine structure of neurofibrillary tangles in progressive supranuclear palsy and suggest that the association between tangles due to straight filaments and tangles due to twisted tubules, so far described in 1 case, is probably exceptional.

引用

页码：147 / 152

页数：6

共 13 条

[1] PROGRESSIVE SUPRANUCLEAR PALSY CASE REPORT WITH PATHOLOGICAL FINDINGS [J].