ENHANCEMENT ACTIVITY OF ANTI-MYCOBACTERIAL SERA IN EXPERIMENTAL MYCOBACTERIUM-BOVIS (BCG) INFECTION IN MICE

被引：31

作者：

FORGET, A

BENOIT, JC

TURCOTTE, R

GUSEWCHARTRAND, N

机构：

[1] ARMAND FRAPPIER INST, LAVAL, QUEBEC, CANADA

[2] UNIV MONTREAL, FAC MED, DEPT MICROBIOL & IMMUNOL, MONTREAL 101, QUEBEC, CANADA

来源：

INFECTION AND IMMUNITY | 1976年 / 13卷 / 05期

关键词：

D O I：

10.1128/IAI.13.5.1301-1306.1976

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

The passive transfer of rabbit anti-mycobacterial immunoglobulins was directed against living or soluble extracts of M. tuberculosis strain H37Rv, which promotes the multiplication of the BCG strain of M. tuberculosis in the spleen of mice infected with low doses of this latter strain. This enhancing effect was reduced significantly when [rabbit] antisera were absorbed with living BCG. Such treatment led to the removal of all hemagglutinating antibodies when antisera were tested against BCG or H37Rv soluble extracts. It is most probable that the enhancing effect is related to the presence of mycobacterial antibodies.

引用

页码：1301 / 1306

页数：6

共 27 条

[1]

BENOIT J.-C., 1963, REV CANADIENNE BIOL, V22, P437

[2]

BENOIT JC, 1963, ACTA TUBERC PNEUM SC, V43, P125

[3] PRESERVATION OF MYCOBACTERIAL SUSPENSIONS AT -55DEGREESC [J].