白介素-6、白介素-10和MMP-9与不稳定斑块的关系研究进展

被引：11

作者：

张丽丽

刘晓静

王会奇

脱厚珍

机构：

[1] 首都医科大学附属北京友谊医院神经内科

来源：

临床和实验医学杂志 | 2012年 / 11卷 / 18期

关键词：

不稳定斑块; 白介素-6; 白介素-10; MMP-9;

D O I：

暂无

中图分类号：

R743.3 [急性脑血管疾病（中风）];

学科分类号：

1002 ;

摘要：

<正>心脑血管疾病是目前全球最常见死因之一,近年来其患病率和病死率逐步升高,目前已成为导致我国人群死亡的主要疾病。大量研究表明,易损斑块脱落和破裂导致动脉管腔血栓形成是造成缺血事件的主要机制[1]。而越来越多的报道显示缺血性脑卒中患者30%由颈动

引用

页码：1513 / 1514+1516 +1516

页数：3

共 10 条

[1] 脑梗死患者血清白介素-6、白介素-8、肿瘤坏死因子-α及白介素-1β水平的研究 [J].

崔丽 ;

郑惠民 ;

陶沂 ;

王晔 ;

张仁琴 .

中国综合临床, 2002, (12) :31-32

[2] 动脉粥样硬化易损斑块的生物学标志物 [J].

冯刚 ;

胡长林 .

国际脑血管病杂志, 2010, (09) :696-701

[3] The vulnerable and unstable atherosclerotic plaque [J].

Fishbein, Michael C. .

CARDIOVASCULAR PATHOLOGY, 2010, 19 (01) :6-11

[4] Interleukin-10 from transplanted bone marrow mononuclear cells contributes to cardiac protection after myocardial infarction [J].

Burchfield, Jana S. ;

Iwasaki, Masayoshi ;

Koyanagi, Masamichi ;

Urbich, Carmen ;

Rosenthal, Nadia ;

Zeiher, Andreas M. ;

Dimmeler, Stefanie .

CIRCULATION RESEARCH, 2008, 103 (02) :203-211

[5] Elevated matrix metalloproteinase-9 associated with stroke or cardiovascular death in patients with carotid stenosis [J].

Eldrup, Nikolaj ;

Gronholdt, Marie-Louise Moes ;

Sillesen, Henrik ;

Nordestgaard, Borge G. .

CIRCULATION, 2006, 114 (17) :1847-1854

[6]

Diffuse and Active Inflammation Occurs in Both Vulnerable and Stable Plaques of the Entire Coronary Tree[J] . Alessandro Mauriello,Giuseppe Sangiorgi,Stefano Fratoni,Giampiero Palmieri,Elena Bonanno,Lucia Anemona,Robert S. Schwartz,Luigi Giusto Spagnoli.Journal of the American College of Cardiology . 2005 (10)

[7]

Overexpression of MMP9 and Tissue Factor in Unstable Carotid Plaques Associated with Chlamydia pneumoniae, Inflammation, and Apoptosis[J] . Sebastian Stintzing,Peter Heuschmann,Letterio Barbera,Matthias Ocker,Andreas Jung,Thomas Kirchner,Daniel Neureiter.Annals of Vascular Surgery . 2005 (3)

[8]

Regulation of matrix metalloproteinases: An overview[J] . Sajal Chakraborti,Malay Mandal,Sudip Das,Amritlal Mandal,Tapati Chakraborti.Molecular and Cellular Biochemistry . 2003 (1)

[9]

Inflammation, obesity, stress and coronary heart disease: is interleukin-6 the link?[J] . John S Yudkin,Meena Kumari,Steve E Humphries,Vidya Mohamed-Ali.Atherosclerosis . 2000 (2)

[10] Elevated levels of interleukin-6 in unstable angina [J].

Biasucci, LM ;

Vitelli, A ;

Liuzzo, G ;

Altamura, S ;

Caligiuri, G ;

Monaco, C ;

Rebuzzi, AG ;

Ciliberto, G ;

Maseri, A .

CIRCULATION, 1996, 94 (05) :874-877

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