心肌细胞凋亡与梗死的研究进展

被引：7

作者：

郝言杰

王元书

解砚英

牟艳玲

机构：

[1] 山东省医学科学院药物研究所

来源：

食品与药品 | 2009年 / 11卷 / 01期

关键词：

细胞凋亡; 心肌缺血; 心肌梗死;

D O I：

暂无

中图分类号：

R542.22 [];

学科分类号：

摘要：

缺血导致的心肌梗死发病过程中伴随着心肌细胞凋亡。研究表明,抑制或减少心肌细胞凋亡能阻止心肌梗死后心室重构和改善心功能。本文综述了细胞凋亡存在于心肌梗死的依据、相关的凋亡调控因子及其信号转导途径,以及减少心肌细胞凋亡的治疗方法,主要包括基因治疗、干细胞移植、天然产物活性成分治疗和联合治疗。

引用

页码：58 / 62

页数：5

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