肠道菌群在肝胆疾病中的作用机制

被引：26

作者：

韩美林

龚振华

机构：

[1] 上海交通大学附属儿童医院普外科

来源：

临床肝胆病杂志 | 2017年 / 33卷 / 02期

关键词：

肠杆菌科; 肝疾病; 胆道疾病; 基因组学; 综述;

D O I：

暂无

中图分类号：

R575 [肝及胆疾病];

学科分类号：

100201 [内科学];

摘要：

肠道菌群是人体最大的微生物群体,参与机体多种生理过程,肠道菌群紊乱与人类多种疾病有关。由于肝脏和胃肠道之间相互作用、相互影响,肠道菌群在肝胆疾病的发生发展过程中发挥重要作用。用宏基因组学研究能更全面更系统地了解肠道菌群特征及其对机体健康和疾病的影响。介绍了非酒精性脂肪性肝病、肝硬化、肝细胞癌及自身免疫性肝病患者肠道菌群的变化及其相关作用机制的研究进展。

引用

页码：384 / 388

页数：5

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