脂蛋白相关磷脂酶A2与冠心病的相关性研究进展

被引：11

作者：

何德化

李卫华

机构：

[1] 福建医科大学附属厦门第一医院心内科

来源：

心血管病学进展 | 2008年 / 01期

关键词：

脂蛋白相关性磷脂酶A2; 冠心病; 动脉粥样硬化;

D O I：

暂无

中图分类号：

R541.4 [冠状动脉（粥样）硬化性心脏病（冠心病）];

学科分类号：

摘要：

血浆脂蛋白相关磷脂酶A2(LP-PLA2)由成熟的巨噬细胞和淋巴细胞合成和分泌,又称血小板活化因子乙酰水解酶(PAF-AH),在血浆中主要与低密度脂蛋白结合。近年来,越来越多研究表明在冠心病的发病机制及预防性治疗上,LP-PLA2是一个新的有待研究的因子,其在循环中的含量和活性与冠状动脉事件风险存在正相关,可能成为冠心病治疗的新靶点。

引用

页码：57 / 60

页数：4

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