TIMI、PURSUIT和GRACE评分对急诊非ST段抬高急性冠脉综合征患者风险预测的比较

被引:12
作者
戴瑄
胡春林
李欣
董德坤
魏红艳
廖晓星
詹红
机构
[1] 中山大学附属第一医院急诊科
关键词
NSTE-ACS; 胸痛; TIMI风险评分; GRACE风险评分; PURSUIT风险评分; 风险分层;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
1002 ; 100201 ;
摘要
目的探讨NSTE-ACS评分GRACE、PURSUIT和TIMI在急诊非ST段抬高急性冠脉综合征(NSTE-ACS)患者风险预测上的价值。方法在PubMed上检索TIMI、PURSUIT和GRACE风险评分对NSTE-ACS患者风险预测的研究。比较不同评分对患者院内、短期(30-day)、长期(360-day)的心血管事件的预测效果。运用χ2检验和威尔克森统计值进行统计分析。结果共有8个研究符合检索条件,共计25 247例NSTE-ACS患者被正式评估。依据TIMI、PURSUIT和GRACE评分患者被相对地划分为低危组、中危组和高危组。院内心血管事件发生率在各评分、各组别间差异无统计学意义(P>0.05)。30 d内的主要心血管风险预测,对于低、中危组患者,TIMI评分优于GRACE和PURSUIT(P<0.05);但对于高危组患者,PURSUIT评分预测效果较好(P<0.05)。1年内主要心血管风险预测,低危组内各评分未见统计学差异(P>0.05),TIMI和PURSUIT评分对中危组患者的风险预测优于GRACE(P<0.05);对于高危组,PURSUIT和GRACE的风险预测效果优于TIMI(P<0.05)。结论 TIMI风险评分适用于NSTE-ACS患者的院内、短期和长期心血管事件的预测,但对于30 d内主要心血管事件风险的预测PURSUIT评分优于TIMI和GRACE。高危组1年内主要心血管事件风险的预测,GRACE评分优于PURSUIT和TIMI。
引用
收藏
页码:1364 / 1368
页数:5
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