大黄资源化学研究进展与利用策略

被引：96

作者：

陈艳琰 ^{[1
]}

唐于平 ^{[1
]}

陈嘉倩 ^{[2
]}

曹玉洁 ^{[2
]}

段金廒 ^{[2
]}

机构：

[1] 陕西中医药大学药学院

[2] 南京中医药大学江苏省中药资源产业化过程协同创新中心

来源：

中草药 | 2018年 / 49卷 / 21期

关键词：

大黄; 资源化学; 利用策略; 功效偏向性; 非药用部位;

D O I：

暂无

中图分类号：

R282.71 [植物药];

学科分类号：

100705 [微生物与生化药学];

摘要：

大黄是我国重要的大宗中药材之一,也是多功效、多品种、多道地产区中药材的典型代表。系统归纳了大黄的资源性化学成分,并基于不同品种、不同产地、不同采收期、不同组织器官分析了大黄资源化学研究进展,据此提出了关注地域变化与把握采收时节,不同品种的"功效偏向性"应用、非药用部位利用、资源性成分的高值化发展等大黄资源化学利用途径与策略,为大黄资源的综合开发与利用提供重要参考。

引用

页码：5170 / 5178

页数：9

共 33 条

[1]

药用大黄地上部分化学成分及生物活性研究 [D].

咸婧 .

中国中医科学院,

2017

[2]

中国植物志.[M].黄成就等编著;中国科学院中国植物志编辑委员会编.科学出版社.1998,

[3]

Influence of the drying method on the bioactive compounds and pharmacological activities of rhubarb [J].

Sun, Jiachen ;

Wu, Yueting ;

Dong, Shengjie ;

Li, Xia ;

Gao, Wenyuan .

JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE, 2018, 98 (09) :3551-3562

[4]

Profiling and analysis of multiple compounds in rhubarb decoction after processing by wine steaming using UHPLC–Q‐TOF‐MS coupled with multiple statistical strategies.[J].Tingting Zhu;Xiao Liu;Xiaoli Wang;Gang Cao;Kunming Qin;Ke Pei;Hui Zhu;Hao Cai;Minjie Niu;Baochang Cai.Journal of Separation Science.2016, 15

[5]

The synergism mechanism of Rhubarb Anthraquinones on constipation elucidated by comparative pharmacokinetics of Rhubarb extract between normal and diseased rats [J].

Gong, Xiao-hong ;

Li, Yan ;

Zhang, Ruo-qi ;

Xie, Xiao-fang ;

Peng, Cheng ;

Li, Yun-xia .

EUROPEAN JOURNAL OF DRUG METABOLISM AND PHARMACOKINETICS, 2015, 40 (04) :379-388

[6]

Active Compounds of Rhubarb Root and Rhizome in Animal Model Experiments of Focal Cerebral Ischemia.[J].Ai-ju Liu;Liang Song;Yan Li;Xiao-guang Zhang;Zi-xian Chen;Li-bo Huang;Hong-feng Zhang;Guo-qing Zheng;Honglin Luo.Evidence-Based Complementary and Alternative Medi.2015,

[7]

The anthraquinone rhein exhibits synergistic antibacterial activity in association with metronidazole or natural compounds and attenuates virulence gene expression in Porphyromonas gingivalis [J].

Azelmat, Jabrane ;

Larente, Jade Fournier ;

Grenier, Daniel .

ARCHIVES OF ORAL BIOLOGY, 2015, 60 (02) :342-346

[8]

Rhubarb root and rhizome-based Chinese herbal prescriptions for acute ischemic stroke: A systematic review and meta-analysis [J].

Lu, Lin ;

Li, Hui-qin ;

Fu, Deng-lei ;

Zheng, Guo-qing ;

Fan, Ji-ping .

COMPLEMENTARY THERAPIES IN MEDICINE, 2014, 22 (06) :1060-1070

[9]

Prediction of Human Pharmacokinetics from Preclinical Information of Rhein, an Antidiabetic Nephropathy Drug, Using a Physiologically Based Pharmacokinetic Model [J].

Hao, Kun ;

Qi, Qu ;

Wan, Ping ;

Zhang, Jingwen ;

Hao, Haiping ;

Liang, Yan ;

Xie, Lin ;

Wang, Guangji ;

Sun, Jianguo .

BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2014, 114 (02) :160-167

[10]

The distinct mechanisms of the antitumor activity of emodin in differenttypes of cancer (Review).[J].Wei-Tian Wei;Sheng-Zhang Lin;Dian-Lei Liu;Zhao-Hong Wang.Oncology Reports.2013, 6

← 1 2 3 4 →