糖尿病心肌病线粒体损伤的研究进展

被引：17

作者：

余薇 ^{[1
,2
]}

刘超 ^{[1
]}

吴基良 ^{[2
]}

机构：

[1] 湖北科技学院糖尿病与心脑血管湖北省重点实验室

[2] 湖北科技学院药学院药理学教研室

来源：

中国药理学通报 | 2013年 / 12期

关键词：

糖尿病心肌病; 线粒体损伤; 能量代谢异常; 氧化应激; 凋亡; 心磷脂;

D O I：

暂无

中图分类号：

R587.2 [糖尿病性昏迷及其他并发症]; R542.2 [心肌疾病];

学科分类号：

100201 [内科学];

摘要：

糖尿病心肌病(diabetic cardiomyopathy,DCM)的发病机制非常复杂,该文就DCM发病机制中线粒体损伤导致线粒体能量代谢异常、ROS产生增加、线粒体依赖性的凋亡途径激活、线粒体的分裂和融合紊乱以及心磷脂含量及结构改变的研究进展做一综述。

引用

页码：1651 / 1654

页数：4

共 11 条

[1]

糖尿病心肌病与过氧化物增殖体激活受体 [J].

董世芬 ;

洪缨 ;

孙建宁 .

中国药理学通报, 2010, 26 (08) :1117-1120

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[3]

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