肝脏免疫与慢性乙型肝炎抗病毒治疗

被引:10
作者
王福生
陈威巍
机构
[1] 解放军第三○二医院生物治疗研究中心
关键词
肝; 免疫学; 肝炎,乙型; 治疗,抗病毒;
D O I
暂无
中图分类号
R51 [传染病];
学科分类号
100201 [内科学];
摘要
慢性乙型肝炎患者体内发生的天然免疫和特异性免疫以及对HBV的免疫耐受,这些可能是病毒持续复制和肝脏慢性炎症的主要原因;在核苷类似物及干扰素抗病毒治疗时,肝脏本身的抗病毒免疫反应对治疗的应答起着决定作用,为清除病毒,达到治愈目标,对慢性乙型肝炎进行抗病毒治疗与免疫治疗联合,调整肝脏免疫耐受状态,增强抗病毒免疫应答,同时避免发生肝脏的免疫损害,具体方案有待研究
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