神经酰胺在非酒精性脂肪性肝病中的作用研究进展

被引：1

作者：

刘浩雷

阳学风

机构：

[1] 南华大学附属南华医院消化内科

来源：

现代医药卫生 | 2015年 / 31卷 / 02期

关键词：

肝病; 乙醇; 脂肪类/代谢; 神经酰胺类; 胰岛素; 细胞凋亡; 综述;

D O I：

暂无

中图分类号：

R575.5 [肝代谢障碍];

学科分类号：

1002 ; 100201 ;

摘要：

<正>非酒精性脂肪性肝病(NAFLD)在欧美国家已取代病毒性肝炎,成为最主要的肝病[1]。近年来研究表明,神经酰胺能阻断胰岛素信号转导,诱发胰岛素抵抗(IR)和炎性反应,提示神经酰胺可能对NAFLD的发病起着重要的作用[2-3]。因此,本文就近年来神经酰胺与NAFLD的研究作一综述。

引用

页码：217 / 220

页数：4

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