左旋布比卡因和甲磺酸罗哌卡因体外的抑菌作用

被引：5

作者：

薛昀

吴新民

张生锁

赵敏

严岩

机构：

[1] 北京大学第一医院麻醉科

来源：

中华麻醉学杂志 | 2005年 / 04期

关键词：

左旋布比卡因; 甲磺酸; 变形杆菌; 粪肠球菌; 罗呱卡因; 盐酸布比卡因; 布比卡因盐酸盐;

D O I：

暂无

中图分类号：

R96 [药理学];

学科分类号：

100602 ; 100706 ;

摘要：

<正>硬膜外麻醉中注射器被细菌感染的机率接近5%,穿刺针被细菌感染的机率为17%。病人自控硬膜外镇痛时,硬膜外导管留置时间延长,增加了细菌感染的风险。盐酸布比卡因和盐酸罗哌卡因有抑菌作用。而左旋布比卡因和甲磺酸罗哌卡因对细菌生长的影响尚未定论。本研究拟比较这四种药物对大肠杆菌(ATCC 25922)、绿脓杆菌(ATCC 27853)、金黄色葡萄球菌(ATCC 25923)、表面葡萄球菌、粪肠球菌和变形杆菌生长的影响,为临床研究提供参考。

引用

页码：293 / 294

页数：2

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