喜树碱类药物作用机制及其耐药现状的研究进展

Camptothecins:A review of their chemo-therapeutic potential..Ulukan H and Swaan PW;.Drugs.2002,

Effect of Pglyco-protein expression on the accumulation and cytotoxicity of topotecan(SK&F104864);a new camptothecin analogue..Hendricks CB;Rouinsky EK;Grochow LB;et al;.Cancer Res.1992,

Carboxylesterase-mediatedsensitization of human tumor cells to CPT-11 cannot override AB-CG2-mediated drug resistance ontribution of c-erbB-2 and topoi-someraseⅡalpha to chemoresistance in ovarian cancer..Hengstler JG;Lange J;Kett A;et al;.CancerRes.1999,

Novel missense mutation ofthe DNA topoisomerase I gene in SN-38-resistant DLD-1 cells..Arakawa Y;Suzuki H;Saito S;et al;.Mol Cancer Ther.2006,

Camptothecins:A review of their chemo-therapeutic potential..Ulukan H and Swaan PW;.Drugs.2002,

Effect of Pglyco-protein expression on the accumulation and cytotoxicity of topotecan(SK&F104864);a new camptothecin analogue..Hendricks CB;Rouinsky EK;Grochow LB;et al;.Cancer Res.1992,

Carboxylesterase-mediatedsensitization of human tumor cells to CPT-11 cannot override AB-CG2-mediated drug resistance ontribution of c-erbB-2 and topoi-someraseⅡalpha to chemoresistance in ovarian cancer..Hengstler JG;Lange J;Kett A;et al;.CancerRes.1999,

Novel missense mutation ofthe DNA topoisomerase I gene in SN-38-resistant DLD-1 cells..Arakawa Y;Suzuki H;Saito S;et al;.Mol Cancer Ther.2006,