肾小管上皮间充质转化与肾脏纤维化

被引：37

作者：

王来亮 ^{[1
]}

罗群 ^{[2
]}

机构：

[1] 宁波大学医学院

[2] 宁波市第二医院肾内科

来源：

中国病理生理杂志 | 2014年 / 30卷 / 10期

关键词：

上皮间充质转化; 肾小管间质纤维化; 信号转导;

D O I：

暂无

中图分类号：

R692.9 [其他疾病];

学科分类号：

100221 [泌尿外科学];

摘要：

<正>肾脏纤维化是所有慢性肾脏疾病(chronic kidney disease,CKD),包括原发性、继发性肾小球疾病,肾小管间质和血管疾病以及肾移植慢性排斥性病变发展至终末期肾脏病共同的最终通路。目前认为,肾脏纤维化是不可逆的进行性病变,最终需透析治疗或肾移植,对患者、家庭及社会造成沉重的负担。尽管世界各国肾脏病学者做了大量的工作,但目前对肾脏纤维化的发病机制仍缺乏全面认识,严重阻

引用

页码：1910 / 1914+1920 +1920

页数：6

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