高龄非ST段抬高急性冠状动脉综合征患者冠状动脉内支架术疗效

被引:5
作者
蒋利
沈卫峰
张建盛
倪钧
机构
[1] 上海第二医科大学附属瑞金医院心脏科
关键词
冠状动脉综合征; 支架; 老年; 预后;
D O I
暂无
中图分类号
R541.4 [冠状动脉(粥样)硬化性心脏病(冠心病)];
学科分类号
摘要
目的 :观察 75岁以上非ST段抬高急性冠状动脉 (冠脉 )综合征患者选择性冠脉内支架术的安全性和远期预后。  方法 :连续 3 2 3例行选择性冠脉内支架术的非ST段抬高急性冠脉综合征患者 ,其中≥ 75岁患者 79例为高龄组 ,<75岁患者 2 44例为对照组。比较两组患者手术结果和远期预后。  结果 :两组支架术成功率和手术并发症率差异无显著性。随访期内 ,两组心绞痛复发、硝酸酯类药物停用、再入院、心功能改善、再次血运重建和病死率均无显著性差异 ,但高龄组心脏事件发生率较对照组显著减少 (15 7%vs .2 8 7% ,P =0 0 2 9)。多因素分析显示 ,年龄不是非ST段抬高急性冠脉综合征患者远期心脏事件的独立预测因素。  结论 :高龄非ST段抬高急性冠脉综合征患者选择性冠脉内支架术有良好的疗效和安全性 ,远期心脏事件发生率较年轻患者少。
引用
收藏
页码:30 / 32
页数:3
相关论文
共 7 条
  • [1] Optimal treatment of acute coronary syndromes—an evolving strategy. Boden WE,McKay RG. The New England Journal of Medicine . 2001
  • [2] Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein Ⅱb/Ⅲa inhibitor tirofiban. Cannon CP,Weintraub WS,Demopoulos LA,et al. The New England Journal of Medicine . 2001
  • [3] Optimal timing for coronary stenting in unstable angina. Shen WF,Zhang RY,Shen Y,et al. Chinese Medical Journal . 2001
  • [4] Factors associated with failure of medical therapy in patients with unstable angina and non-Q wave myocardial infarction: a TIMI ⅢB database study. Stone PH,Thompson B,Zaret BL,et al. European Heart Journal . 1999
  • [5] Early angioplasty in acute coronary syndromes without persistent ST-segment elevation improves outcome but increases the need for six-month repeat revascularization: an analysis of the PURSUIT Trial. Ronner E,Boersma E,Laarman GJ,et al. Journal of the American College of Cardiology . 2002
  • [6] Early percutaneous coronary intervention, platelet inhibition with eptifibatide, and clinical outcomes in patients with acute coronary syndromes.PURSUIT Investigators. Kleiman NS,Lincoff AM,Flaker GC,et al. Circulation . 2000
  • [7] ACC/AHA guidelines for the management of patients with unstable angina and non-ST-segment elevation myocardial infarction: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Braunwald E,Antman EM,Beasley JW,et al. Journal of the American College of Cardiology . 2000