动脉粥样硬化血管内皮分泌功能失调与平滑肌细胞增殖

被引：61

作者：

李磊

戴敏

机构：

[1] 安徽中医学院药学院,安徽省现代中药重点实验室

来源：

中国药理学通报 | 2010年 / 02期

关键词：

动脉粥样硬化; 血管内皮细胞; 平滑肌细胞; 生长因子; 细胞因子; 血管活性物质; 增殖;

D O I：

暂无

中图分类号：

R543 [血管疾病];

学科分类号：

100201 [内科学];

摘要：

血管内皮细胞和平滑肌细胞是血管壁两种主要细胞,两者在结构上和功能上有着密切的关系,动脉粥样硬化的发生源于循环因子和血管壁细胞间的相互作用,内皮细胞损伤等所导致的分泌功能失调和平滑肌细胞的异常增殖而引起的血管腔狭窄和痉挛是动脉粥样硬化等多种血管疾病发生发展的共同病理基础。本文从动脉粥样硬化病理状态下血管内皮分泌的生长因子、细胞因子、血管活性物质对平滑肌细胞增殖影响的最新研究进展做一综述。

引用

页码：155 / 158

页数：4

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