腰椎间盘退变对软骨终板生物力学特性影响的有限元分析

被引：30

作者：

赵亮 ^{[1
]}

闫广华 ^{[2
]}

瞿东滨 ^{[3
]}

赵卫东 ^{[4
]}

史占军 ^{[1
]}

张美超 ^{[4
]}

机构：

[1] 南方医科大学南方医院关节与骨病外科

[2] 成都医学院第一附属医院医务科

[3] 南方医科大学南方医院脊柱骨科

[4] 南方医科大学人体解剖学教研室,广东省医学生物力学重点实验室

来源：

中国临床解剖学杂志 | 2015年 / 33卷 / 04期

基金：

广东省科技计划; 广东省自然科学基金;

关键词：

腰椎; 软骨终板; 腰椎间盘退变; 生物力学;

D O I：

10.13418/j.issn.1001-165x.2015.04.018

中图分类号：

R681.5 [脊柱及背疾病];

学科分类号：

100220 [骨科学];

摘要：

目的研究腰椎终板不同位点的压应力分布规律,分析腰椎间盘退变对软骨终板压应力的影响。方法选取一青壮年男性新鲜尸体的腰椎运动节段标本,螺旋CT机对腰椎运动节段进行连续CT扫描,利用有限元分析方法,建立L4/5运动节段有限元分析模型,在此基础上建立椎间盘退变模型。模拟椎间盘正常状态和椎间盘退变状态,在L4、L5椎体终板上选择具有代表性的结点,分别代表椎体终板正中部、左右侧边缘、后中部和前中部,对上下软骨终板压应力分布进行有限元分析。结果椎间盘退变组较正常组的终板压应力均显著增大,上下终板在轴向加载、前屈、后伸、左旋和右旋加载时椎间盘退变组较正常状态时应力分布均显著增大,具有统计学意义(P<0.05)。结论腰椎椎间盘退变因素对终板的应力分布有明显影响,随着椎间盘退变,椎间盘软骨终板应力显著增大。

引用

页码：455 / 460

页数：6

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