非酒精性脂肪性肝病研究的关切点

被引：8

作者：

曾民德

机构：

[1] 上海交通大学医学院附属仁济医院,上海市消化疾病研究所,上海市脂肪性肝病诊治研究中心

来源：

肝脏 | 2009年 / 14卷 / 04期

关键词：

非酒精性脂肪性肝病; 自然史; 临床流行病学; 纤维化; NAFLD; 脂肪;

D O I：

10.14000/j.cnki.issn.1008-1704.2009.04.015

中图分类号：

R575 [肝及胆疾病];

学科分类号：

1002 ; 100201 ;

摘要：

非酒精性脂肪性肝病(NAFLD)是一门年轻的学科。曾民德教授作为我国脂肪性肝病研究的先驱,结合自己科研成果和临床体会,潜心参阅百余篇文献,总结为"脂肪性肝病研究的关切点"一文。该文从临床流行病学和自然史、病理生理和组织病理、临床评估和无创性诊断、综合处理及药物治疗靶点等方面介绍了NAFLD的研究进展和发展方向。特别是在病理生理方面,对一些新的视点如肠-脑-肝轴和肠-肝轴、脂肪毒、线粒体功能不全和内质网应激等作了入木三分的阐述和评价。对肝脏病工作者,尤其是脂肪性肝病研究的学者这无疑是一篇非常难得的指导性文件。

引用

页码：321 / 324

页数：4

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