神经病理性疼痛药物治疗回顾与展望

被引：23

作者：

杨阳

樊碧发

机构：

[1] 中日友好医院

来源：

中国新药杂志 | 2014年 / 23卷 / 14期

关键词：

神经病理性疼痛; 药物治疗;

D O I：

暂无

中图分类号：

R971 [神经系统药物];

学科分类号：

100115 [医学神经生物学];

摘要：

神经病理性疼痛临床常见且难治,目前被公认的一线药物有抗惊厥药物包括:①加巴喷丁、普瑞巴林、卡马西平等。②三环类抗抑郁药及选择性5-羟色胺和去甲肾上腺素再摄取抑制剂如阿米替林、文拉法辛及度洛西汀等。二线药物包括:①强阿片类药物及弱阿片类药物如吗啡、羟考酮及曲马多等。②利多卡因及辣椒碱等外用药物。③非甾体镇痛消炎药。今后,NMDA受体拮抗剂以及成瘾性更小的丁丙诺非及美沙酮会得到更多应用。

引用

页码：1628 / 1630+1646 +1646

页数：4

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