代谢组学在中药安全性评价中的应用

被引：12

作者：

吴晓敏 ^{[1
,2
]}

韩利文 ^{[2
]}

杨官娥 ^{[1
]}

刘可春 ^{[2
]}

机构：

[1] 山西医科大学药学院

[2] 山东省科学院生物研究所,山东省生物传感器重点实验室

来源：

山东科学 | 2014年 / 27卷 / 02期

关键词：

代谢组学; 中药; 安全性评价; 毒性;

D O I：

暂无

中图分类号：

R288 [中药药事组织];

学科分类号：

100406 [军事预防医学];

摘要：

作为系统生物学的重要组成部分,代谢组学在中药毒性或安全性评价方面表现出很大的应用潜力。本文综述了代谢组学在中药毒性作用的靶器官、中毒剂量、作用机制、生物标志物以及毒性物质基础等研究领域的作用。尽管尚处于发展阶段,但是代谢组学为中药毒性或安全性评价提供了新的思路和研究方法,可作为中药安全性评价的有力补充。

引用

页码：34 / 38

页数：5

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