肺癌患者外周血调节性T细胞和IL-10的检测及其意义

被引:15
作者
翟晋芳
杜凤兰
绳晋雅
郭志娟
机构
[1] 山西省肿瘤医院呼吸一科
关键词
肺癌; CD4+CD25+T细胞; IL-10;
D O I
暂无
中图分类号
R734.2 [肺肿瘤];
学科分类号
100117 [系统生物医学];
摘要
目的:探讨肺癌患者外周血调节性T细胞和IL-10检测的诊断意义及与临床特征相关性。方法:采用流式细胞仪检测60例肺癌患者外周血中CD4+CD25+T细胞的表达水平,同时采用ELISA法检测IL-10的表达水平。并随机选30例健康体检者作为对照组结果:肺癌患者外周血中CD4+CD25+T细胞和IL-10的表达水平明显高于健康对照组(P<0.05);CD4+CD25+T细胞与IL-10的检测结果呈正相关;肺癌患者外周血中CD4+CD25+T细胞和IL-10的表达水平与临床分期有关(P<0.05),与病理类型无关(P>0.05)。结论:检测肺癌患者外周血中CD4+CD25+T细胞和IL-10的表达水平,有助于肺癌患者病情的评估和治疗
引用
收藏
页码:325 / 327
页数:3
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