共 1 条
硫酸乙酰肝素糖蛋白的结构-功能多样性与相关修饰酶群作用
被引:9
作者:
姜笃银
付小兵
盛志勇
机构:
[1] 解放军第医院全军创伤修复重点实验室,解放军第医院全军创伤修复重点实验室,解放军第医院全军创伤修复重点实验室北京,北京,北京
来源:
基金:
国家自然科学基金重点项目;
关键词:
类肝素硫酸蛋白聚糖;
基膜;
细胞外基质;
D O I:
暂无
中图分类号:
R341 [];
学科分类号:
摘要:
The cytokine-receptor- heparin sulfate functional complex combined by cytokines, cytokine receptors, and heparin sulfate chains formed by concatenation of heparin sulfate proteoglycans (HSPG), an important component of extracellular matrix and modified by some relative enzymes, can regulate the density of cytokine receptors and their intracellular signal transduction. This article focused on the regulatory function of this complex. Many morphological abnormalities and diseases occur when the complex is dysfunctional.
引用
收藏
页码:1020 / 1025
页数:6
相关论文